Comprehensive Elements-Thyroid Profile

Comprehensive Iodine Thyroid Profile


Summary: For those persons needing to track their levels of iodine, and the ability of their thyroid to utilize it. This state-of-the-art profile combines an advanced thyroid panel in dried blood spot along with with elements in dried urine. While bromine, arsenic, mercury, and cadmium are known biological toxins, iodine and selenium can potentially be toxic also if dietary intake, including excessive supplementation, is too high. Testing for these elements in urine provides an excellent assessment of overall body burden of toxic elements, and is an indicator of excessive or inadequate intake or supplementation of iodine and selenium.Tests in this profile include:

Elements: (dried urine): Iodine, Bromine, Cadmium, Selenium, Arsenic, Creatinine and Mercury.

Thyroid: (dried blood spot): TSH, fT3, fT4, TPO, Total T4, Thyroglobulin

Price: $295.00

Also known by ZRT LAB Product Name: Comprehensive Elements -Thyroid Profile


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This testing allows practitioner screening for hypo or hyperthyroidism, autoimmune thyroid disease, and monitoring thyroid replacement dosages. Elements allows practitioner to see if an individual has too little or too much of essential nutrients iodine and selenium or for over exposure to bromine, arsenic and mercury. 

Thyroid function can be affected by many factors, including nutritional deficiencies and environmental exposure to certain elements. This profile is designed to help evaluate elemental exposure and thyroid hormone synthesis and the root problems of thyroid disorders and other health issues.

Testing Iodine levels and treatment for both excessive or deficiency is emerging area of science that holds potential for improving your health and longevity.

Testing Iodine

Testing iodine, along with the blood spot tests in this profile, allows the tester to appreciate fully the impact of iodine on thyroid health and this is why:

There will always be limitations to detecting iodine over 24 hr or multiple single point tests (as provided by ZRT) because iodine levels can change somewhat from day to day depending on diet. Overall, if diet remains about the same, levels shouldn’t fluctuate too much. With this caveat, ZRT went one step beyond iodine and developed dried blood spot tests that look at how well iodine is incorporated into the thyroid gland and how it is utilized for thyroid hormone synthesis. ZRT developed thyroid tests in dried blood spot that measure the following analytes associated with iodine: thyroglobulin, total T4, free T4, free T3, TSH, and TPO. Each of these analytes are uniquely associated with iodine.

Thyroglobulin is well recognized as a marker of iodine nutritional status over the past weeks. When iodine levels are low thyroglobulin is poorly iodinated and it spills out of the thyroid follicular lumen into the bloodstream. High levels indicate low iodine status. Iodine supplementation to sufficiency usually returns thyroglobulin to normal levels of less than 10 ng/ml in blood.

When iodine levels are very low, or very high from excessive supplementation (e.g. Iodoral in excess), thyroid hormone synthesis is inhibited and the amount of Total T4 released from the thyroid gland into the bloodstream decreases. Low T4 signals the brain to make more TSH to activate the thyroid gland to make more thyroid hormones, therefore an elevated TSH can be due to iodine levels too low or too high.

Free T4 and free T3 are not as directly related to iodine status, but provide some information about the bioavailable levels of these hormones to systemic tissues throughout the body.

TPO antibodies are important because those individuals positive (Hashimoto’s thyroiditis) for this condition have a compromised thyroid gland that may react adversely to iodine supplementation, causing a person to go from mild subclinical hypothyroid state to one of clinical hypothyroidism that requires thyroid medication.

The lab will email you when your results are ready, generally 3-5 business days after samples are received by the lab.  

  • You will receive information on how to access your results on-line. 
  • Once you have your results, read our Interpreting Results article.
  • Consider consulting with a practitioner for next steps.
  • Knowledge is the key to wellness.

Find out what you need to know and start your path towards recovery today.


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The Canary Club is an educational advisory group with a team of medical advisors headed by Richard Shames, M.D.